Here is my opinion. I worked with WPF and Avalonia UI for a long time and I don't think it is suited for sbox.
Avalonia's main features are: design preview, cross platform support, data binding and css-like hierarchical styles. And even though binding is very good addition, but design preview, cross platform support not needed and advanced styling is very unnecessary.
I think editor UI should be consistent across all editor tools, must have a easy learning curve and good accessibility. Advanced styling would hurt that vision.
Qt on the other hand more strict in this regard. This would make sure that your own tools would still look and work similar to other people tools.
And I don't need XAML. It would be another thing to worry about. Another thing that would break development flow as you would need to constantly switch from XAML to csharp.
I don't see a way Avalonia would help with editor UI development and make it easier and faster. But you all are very welcome to change my mind.